Gerald J Gleich Selected Research

Hypereosinophilic Syndrome (Loeffler Endocarditis)

1/2022	Mepolizumab Reduces Hypereosinophilic Syndrome Flares Irrespective of Blood Eosinophil Count and Interleukin-5.
12/2021	Safety and Efficacy of Mepolizumab in Hypereosinophilic Syndrome: An Open-Label Extension Study.
12/2020	Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial.
2/2013	Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes.
10/2010	Mepolizumab as a corticosteroid-sparing agent in lymphocytic variant hypereosinophilic syndrome.
12/2009	Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
6/2009	Treatment of FIP1L1/PDGFRA-negative hypereosinophilic syndrome with alemtuzumab, an anti-CD52 antibody.
3/2008	Treatment of patients with the hypereosinophilic syndrome with mepolizumab.
6/2006	Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report.
5/2002	Treatment of hypereosinophilic syndrome with imatinib mesilate.

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Gerald J Gleich Research Topics

Disease

10	Hypereosinophilic Syndrome (Loeffler Endocarditis) 01/2022 - 05/2002
10	Asthma (Bronchial Asthma) 12/2020 - 03/2004
9	Eosinophilic Esophagitis 01/2020 - 12/2011
9	Inflammation (Inflammations) 01/2020 - 03/2002
7	Eosinophilia 01/2021 - 05/2002
4	Churg-Strauss Syndrome (Allergic Angiitis) 01/2020 - 06/2006
4	Hypersensitivity (Allergy) 03/2016 - 09/2002
3	Neoplasms (Cancer) 12/2019 - 04/2004
3	Eosinophilia-Myalgia Syndrome 09/2018 - 01/2003
2	Rhinosinusitis 01/2015 - 08/2005
2	Neuroblastoma 11/2011 - 10/2003
2	Atopic Dermatitis (Atopic Eczema) 03/2006 - 11/2003
1	Myeloproliferative Disorders (Myeloproliferative Disorder) 01/2021
1	Polycythemia Vera 12/2019
1	Primary Myelofibrosis (Myelosclerosis) 12/2019
1	Essential Thrombocythemia 12/2019
1	Cough 01/2019
1	Chronic Urticaria 06/2016
1	Esophageal Diseases 09/2015
1	Disease Progression 09/2015
1	Drug Hypersensitivity (Drug Allergy) 08/2015
1	Esophagitis 09/2014
1	Shellfish Hypersensitivity 12/2013
1	Allergic Rhinitis 04/2013
1	Rhinitis 04/2013
1	Experimental Melanoma 11/2011
1	Lymphoma (Lymphomas) 05/2009
1	Bites and Stings (Sting) 02/2009
1	Anaphylaxis (Anaphylactic Shock) 02/2009
1	Sepsis (Septicemia) 09/2008
1	Respiratory Hypersensitivity 03/2008
1	Airway Remodeling 10/2006
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 06/2006
1	Urticaria (Hives) 03/2006
1	Skin Diseases (Skin Disease) 03/2006
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 12/2005
1	Bacterial Infections (Bacterial Infection) 08/2005

Drug/Important Bio-Agent (IBA)

12	mepolizumabIBA 01/2022 - 03/2008
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2002
5	Interleukin-5 (Interleukin 5)IBA 01/2022 - 05/2002
5	Monoclonal AntibodiesIBA 01/2017 - 03/2008
5	Immunoglobulin E (IgE)IBA 03/2016 - 09/2002
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2011
3	Eosinophil Major Basic ProteinIBA 01/2019 - 08/2005
3	GlucocorticoidsIBA 01/2017 - 05/2004
3	AllergensIBA 04/2013 - 03/2003
3	CytokinesIBA 04/2012 - 08/2002
3	Cholinergic Agents (Cholinergics)IBA 11/2011 - 10/2003
2	Biological ProductsIBA 01/2021 - 10/2006
2	Lidocaine (Xylocaine)FDA LinkGeneric 12/2020 - 05/2004
2	Immunoglobulin G (IgG)IBA 01/2020 - 09/2014
2	Heparin (Liquaemin)FDA LinkGeneric 01/2020 - 12/2013
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2019 - 08/2002
2	Tryptophan (L-Tryptophan)FDA Link 09/2018 - 01/2018
2	Omalizumab (Xolair)FDA Link 06/2016 - 09/2014
2	Eosinophil Granule ProteinsIBA 03/2015 - 11/2003
2	Immunoglobulin A (IgA)IBA 09/2014 - 01/2011
2	AntigensIBA 01/2011 - 03/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2010 - 03/2008
2	Nerve Growth Factor (NGF)IBA 08/2009 - 03/2002
2	Imatinib Mesylate (Gleevec)FDA Link 12/2005 - 05/2002
1	Growth Factor ReceptorsIBA 12/2021
1	LigandsIBA 12/2019
1	Cytokine Receptors (Cytokine Receptor)IBA 12/2019
1	Interleukin-3 Receptors (Interleukin 3 Receptor)IBA 12/2019
1	Janus Kinase 2IBA 12/2019
1	GasesIBA 01/2019
1	AmmoniaIBA 01/2019
1	Irritants (Vesicants)IBA 01/2019
1	Sulfur DioxideIBA 01/2019
1	Fatty Acids (Saturated Fatty Acids)IBA 09/2018
1	Prednisolone (Predate)FDA LinkGeneric 01/2017
1	Prednisone (Sone)FDA LinkGeneric 01/2017
1	Eosinophil PeroxidaseIBA 01/2016
1	Contrast MediaIBA 03/2015
1	Immunoglobulin M (IgM)IBA 09/2014
1	Antigen-Antibody Complex (Immune Complex)IBA 09/2014
1	Fluticasone (Cutivate)FDA LinkGeneric 08/2014
1	TropomyosinIBA 12/2013
1	EpitopesIBA 12/2013
1	Indicators and Reagents (Reagents)IBA 09/2012
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 10/2010
1	Alemtuzumab (Campath)FDA Link 06/2009
1	DNA (Deoxyribonucleic Acid)IBA 09/2008
1	Sepharose (Agarose)IBA 08/2008
1	Formaldehyde (Formol)FDA Link 03/2006
1	ParaffinIBA 03/2006
1	estramustine-binding proteinIBA 11/2005
1	OzoneIBA 10/2005
1	Phenobarbital (Luminal)FDA Link 08/2005
1	Bronchodilator Agents (Bronchodilators)IBA 05/2004
1	heparanaseIBA 04/2004

Therapy/Procedure

7	Therapeutics 12/2020 - 05/2004
2	Esophagectomy 09/2014 - 09/2012
1	Oral Administration 01/2020
1	Transplantation 08/2015
1	Microbubbles 03/2015
1	Drug Tapering 08/2014
1	Punctures 09/2008
1	Ligation 09/2008